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More than chromosomes.

Standard IVF genetic testing tells you whether an embryo has the right number of chromosomes. Reticular goes further — using the same data you already have to predict health risks across dozens of traits.

What standard testing misses

PGT-A (preimplantation genetic testing) is now routine in IVF. It screens embryos for chromosomal abnormalities — extra or missing chromosomes — and helps identify which embryos are most likely to result in a healthy pregnancy. But chromosomal problems are just one piece of the picture. Most common diseases — heart disease, type 2 diabetes, certain cancers — aren't caused by a single chromosome error. They're shaped by hundreds or thousands of small genetic variations working together.

What polygenic scores are

A polygenic score adds up genetic signals from across the entire genome to estimate a person's likelihood of developing a given condition. Think of it as a risk forecast built from thousands of small clues rather than a single red flag. Polygenic scores are already used in adult medicine to guide screening and prevention. Reticular applies the same science at the embryo stage — giving families information they've never had access to before.

No new tests required

Reticular works with the genetic data your clinic already collects during PGT-A. There's no additional biopsy, no extra procedure, and no additional wait. We analyze the existing sequencing data and return polygenic scores for a range of traits — so you and your care team can make more informed decisions about which embryo to transfer.

What we screen for

Our polygenic scores cover conditions where genetic risk is well-established and medically actionable, including:

  • Cardiovascular disease
  • Type 2 diabetes
  • Breast and prostate cancer
  • Inflammatory conditions
  • Mental health disorders

Want to learn whether Reticular is available through your clinic, or have questions about how polygenic scores work?

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